Avoid drinking alcohol when taking your medication, since the two can combine to increase your risk of stomach upset. If you need an NSAID , you may need to also take additional medications such as an antacid, a proton pump inhibitor, an acid blocker or cytoprotective agent. Peptic ulcer care at Mayo Clinic. Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission. This content does not have an English version.
This content does not have an Arabic version. Overview Ulcers Open pop-up dialog box Close. Ulcers A peptic ulcer is a sore on the lining of your stomach, small intestine or esophagus. Email address. First Name let us know your preferred name. Last Name. Thank you for subscribing Your in-depth digestive health guide will be in your inbox shortly. Sorry something went wrong with your subscription Please, try again in a couple of minutes Retry.
Request an Appointment at Mayo Clinic. Share on: Facebook Twitter. Show references Kellerman RD, et al. Gastritis and peptic ulcer disease. In: Conn's Current Therapy Elsevier; Accessed July 8, Peptic ulcer disease. American College of Gastroenterology. Peptic ulcers stomach ulcers. Feldman M, et al. Saunders Elsevier; Nehra AK, et al. Proton pump inhibitors: Review of emerging concerns. Mayo Clinic Proceedings. Peptic ulcer disease adult. A rarer complication of stomach ulcers is the lining of the stomach splitting open, known as perforation.
This can be very serious because it enables the bacteria that live in your stomach to escape and infect the lining of your abdomen peritoneum.
This is known as peritonitis. In peritonitis, an infection can rapidly spread into the blood sepsis before spreading to other organs. This carries the risk of multiple organ failure and can be fatal if left untreated. If you have this type of pain, contact your GP immediately. If this isn't possible, call NHS or your local out-of-hours service. Peritonitis is a medical emergency that requires hospital admission. In some cases, surgery may be needed.
In some cases, an inflamed swollen or scarred stomach ulcer can obstruct the normal passage of food through your digestive system. The symptoms of a peptic ulcer can often be vague, manifesting with pain or discomfort in the upper left abdomen as well as heartburn, indigestion, nausea, and gas. In some cases, complications can occur, leading to more severe symptoms.
The overuse of nonsteroidal anti-inflammatory drugs NSAIDs like Advil ibuprofen is one such example where bleeding from a peptic ulcer can turn from mild to severe. There are three serious complications of a peptic ulcer that may require emergency intervention:. Ulcers form when the lining of the stomach or duodenum known as the mucosa and submucosa becomes eroded. Small ulcers may not cause any symptoms, but large ulcers can cause serious bleeding.
Most ulcers occur in the first layer of the inner lining. If the ulcer erodes beyond that, a hole can open that goes all the way through the intestine, causing perforation. A perforation is always considered a medical emergency.
Despite the popular belief that peptic ulcers are caused by spicy foods or stress, most peptic ulcers are caused by infection by a bacterium called Helicobacter pylori H. Most ulcers can be treated with medications, including antibiotics. But surgery may be needed in some cases, including cauterization in which tissue is burnt to close off a bleeding blood vessel.
Most peptic ulcers are not a medical emergency and can be treated on an outpatient basis. If there has been a perforation, severe internal bleeding, or obstruction, you may need to seek immediate medical care. Warning signs of a medical emergency include:. If left untreated, intestinal perforation and internal bleeding can lead to shock , coma, multiple organ failure, and death;.
Perforation affects around five of every , people with peptic ulcer in the United States, while internal bleeding affects up to 57 of , people with peptic ulcers. Both account for the majority of peptic ulcer-related deaths.
If you develop any of the signs of these peptic ulcer-related complications, seek help without delay. Gas pain? Stool issues? Sign up for the best tips to take care of your stomach. Diagnosis and treatment of perforated or bleeding peptic ulcers: WSES position paper. World J Emerg Surg. Peptic ulcers stomach ulcers.
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